Clinical and behavioral correlates in adult methamphetamine users with childhood exposure to household drug and alcohol use
Abstract
Aims: To describe and compare methamphetamine (MA) users with and without a family history of alcohol or drug () use in the household.
Design: A total of 1144 Thai-speaking MA users in Thailand were recruited for a cohort study. Cross-sectional baseline data were analyzed according to their exposure to FAOD use (FAOD+/FAOD-). The Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) was utilized to collect baseline socio-demographic information and variables known to be associated with the impact of FAOD use.
Findings: FAOD+ participants had lower average years of education (p<0.01), fewer average months of employment in the past year (p<0.01) and reported higher rates of self-harm experience (p<0.001), gambling (p=0.018) and antisocial personality disorder (p=0.015). FAOD+ participants had more severe clinical, adverse consequences. FAOD+ significantly predicted episodes of lifetime MA use (R2 =0.004, p=0.032), the largest number of drinks ever had in a 24-hour period (R2 =0.01, p=0.001), paranoid experiences ([OR]=1.090, p=0.004), alcohol dependence ([OR]=1.112, p=0.001) and antisocial personality disorder ([OR]=1.139, p=0.015). FAOD+ participants who were exposed to alcohol only were more likely to report a significantly higher number of drinks ever had in a 24-hour periods (p<0.005). Similarly, FAOD+ participants who were exposed to MA use only were significantly more likely to report more frequent use of MA (p<0.005).
Conclusions: FAOD+ participants were characterized by a generally more severe clinical presentation than FAOD- participants. Moreover, we show the specificity of drug type mattered, with family exposure of alcohol and MA associated with greater subsequent use of the respective drugs.
In consideration of publishing this article the authors transfer, assign, or otherwise convey all copyright ownership to the International Journal of Alcohol and Drug Research. By this transfer, the article becomes the property of the International Journal of Alcohol and Drug Research and may not be published elsewhere without written permission from the journal.
This transfer of copyright also implies transfer of rights for printed, electronic, microfilm, and facsimile publication. The author(s) will receive no royalty or other monetary compensation for transferring the copyright of the article to the International Journal of Alcohol and Drug Research. IJADR, in turn, grants each author the right to republish the article, without paying royalties to IJADR, in any book of which he or she is the author or editor, subject to the express conditions that (a) the author notify the International Journal of Alcohol and Drug Research in writing of this republication and (b) a credit line attributes the original publication to the International Journal Of Alcohol and Drug Research.
Licence:
Articles are licenced with a Creative Commons License Deed -- you are free to share articles but must give appropriate attribution, may not use for commercial purposes or distribute modified works. See CC/BY-NC/ND/4.0/.
Author Agreement:
As the submitting author, and on behalf of all of the manuscript authors I agree with the terms above relating to the copyright transfer of the manuscript to the International Journal of Alcohol and Drug Research.
